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Table 8 Levels of BHB associated with AC-1202, fasting, and dietary regimens

From: Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

Intervention Average BHB
levels, mM
Notes Reference
12 hour fast 0.08 – 0.1 Fasting level on typical diet This study, [47, 48]
AC-1202 (20 grams) 0.36 2 hour post-dose levels This study
Low carbohydrate diet 0.4 – 0.65 Low carbohydrate diets ranging from 4–10% carbohydrate [4548]
Ketogenic diet 0.3 – 1.6 Ketogenic diets given to children with refractive epilepsy [49, 50]
Starvation 4 – 8 5–6 weeks of complete starvation [51]
Diabetic ketoacidosis 9 – 10 Insulin deficiency and elevated levels of counter-regulatory hormones [52]