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Table 8 Levels of BHB associated with AC-1202, fasting, and dietary regimens

From: Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

Intervention

Average BHB

levels, mM

Notes

Reference

12 hour fast

0.08 – 0.1

Fasting level on typical diet

This study, [47, 48]

AC-1202 (20 grams)

0.36

2 hour post-dose levels

This study

Low carbohydrate diet

0.4 – 0.65

Low carbohydrate diets ranging from 4–10% carbohydrate

[45–48]

Ketogenic diet

0.3 – 1.6

Ketogenic diets given to children with refractive epilepsy

[49, 50]

Starvation

4 – 8

5–6 weeks of complete starvation

[51]

Diabetic ketoacidosis

9 – 10

Insulin deficiency and elevated levels of counter-regulatory hormones

[52]