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Table 6 Cardiac level (pg/mg protein) of inflammatory cytokine (IL-1beta, IL-6, TNF-alpha and MCP-1), and anti-inflammatory cytokine (IL-4 and IL-10) in non-diabetic (Non-DM), diabetic mice consumed normal diet (DM), 2% caffeic acid (CA) or ellagic acid (EA) at 12 week.

From: Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice

 

Non-DM

DM

DM+CA

DM+EA

IL-1beta

15 ± 2a

331 ± 26c

234 ± 25b

227 ± 23b

IL-6

18 ± 3a

411 ± 30d

323 ± 28c

226 ± 26b

TNF-alpha

19 ± 4a

386 ± 21d

305 ± 25c

245 ± 19b

MCP-1

16 ± 3a

278 ± 22d

225 ± 16c

192 ± 14b

IL-4

14 ± 4a

230 ± 24b

227 ± 21b

219 ± 26b

IL-10

17 ± 3a

209 ± 30b

198 ± 19b

204 ± 29b

  1. a-dMeans in a row without a common letter differ, p < 0.05.
  2. Data are mean ± SD, n = 15.