Figure 1From: Early responses of insulin signaling to high-carbohydrate and high-fat overfeedingPhosphorylation of IRS-1. Tyrosine (A) and Serine (B) phosphorylation of IRS-1 in skeletal muscle following Eucaloric feeding (EC), high-carbohydrate overfeeding (HC), and high-fat overfeeding (HF). HC overfeeding increased tyrosine phosphorylation of IRS-1 compared to EC feeding. HF overfeeding increased serine phosphorylation of IRS-1 compared to EC feeding.Back to article page