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Figure 2 | Nutrition & Metabolism

Figure 2

From: Alcohol-induced decrease in muscle protein synthesis associated with increased binding of mTOR and raptor: Comparable effects in young and mature rats

Figure 2

Effect of acute alcohol intoxication on the total amount and phosphorylation of ribosomal protein S6 in skeletal muscle from young and mature rats. Groups are the same as described in Figure 1. Gastrocnemius was collected 2.5 h after administration of alcohol or saline (control). Insert at top: representative Western blots of Ser240/Ser244-phosphorylated (P) S6 and total S6 protein in muscle. Top and middle graphs: densitometric analysis of immunoblots of Ser240/244-phosphorylated S6 and total S6, respectively. Bottom graph: ratio of phosphorylated (P) to total S6 protein in muscle. Values (means ± SEM) are expressed relative to the young saline-treated control group. Sample size was 10, 10, 6, 7, 9, and 9 for the six groups, respectively. Values with different letters are significantly different from each other, P < 0.05. Values which share a common letter are not statistically different.

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