| |
Young
|
Mature – Low Dose EtOH*
|
Mature – High Dose EtOH
|
|---|
| |
Control
|
Alcohol
|
Control
|
Alcohol
|
Control
|
Alcohol
|
|
IGFBP-1, AU/L32
|
1.00 ± 0.08a
|
1.78 ± 0.22b
|
0.91 ± 0.17a
|
1.21 ± 0.19a
|
0.94 ± 0.09a
|
2.68 ± 0.26c
|
|
IGFBP-2, AU/L32
|
1.00 ± 0.08a
|
0.64 ± 0.05b
|
0.45 ± 0.08b
|
0.52 ± 0.05b
|
0.47 ± 0.06b
|
0.49 ± 0.09b
|
|
IGFBP-3, AU/L32
|
1.00 ± 0.11
|
1.05 ± 0.15
|
0.87 ± 0.11
|
0.79 ± 0.09
|
0.84 ± 0.08
|
0.78 ± 0.14
|
|
IGFBP-4, AU/L32
|
1.00 ± 0.07
|
1.18 ± 0.12
|
0.90 ± 0.08
|
0.97 ± 0.07
|
0.89 ± 0.11
|
0.95 ± 0.09
|
|
ALS, AU/L32
|
1.00 ± 0.09a
|
0.68 ± 0.07b
|
1.11 ± 0.11a
|
1.01 ± 0.11a
|
1.08 ± 0.09a
|
0.61 ± 0.07b
|
- Values are means ± SEM where the sample size was 10, 10, 6, 7, 9, and 9 for the six groups, respectively. *Mature rats were administered either "low" dose alcohol (75 mmol/kg) or "high" dose alcohol (90 mmol/kg); young rats were injected with 75 mmol/kg. Abundance of IGFBP-5 was below the detection limit for liver in all animals and data are not reported. Values with different letters for a particular hormone are significantly different from each other, P < 0.05. Values with the same letter are not significantly different.
