|
Young
|
Mature – Low Dose EtOH*
|
Mature – High Dose EtOH
|
---|
|
Control
|
Alcohol
|
Control
|
Alcohol
|
Control
|
Alcohol
|
IGFBP-3, AU/L32
|
1.00 ± 0.08
|
0.87 ± 0.11
|
0.81 ± 0.12
|
0.83 ± 0.11
|
0.79 ± 0.11
|
0.77 ± 0.15
|
IGFBP-4, AU/L32
|
1.00 ± 0.12
|
0.95 ± 0.12
|
1.24 ± 0.21
|
1.18 ± 0.19
|
1.14 ± 0.12
|
1.13 ± 0.14
|
IGFBP-5, AU/L32
|
1.00 ± 0.06a
|
0.66 ± 0.06b
|
0.84 ± 0.07a
|
0.85 ± 0.06ab
|
0.89 ± 0.08a
|
0.49 ± 0.07b
|
- Values are means ± SEM where the sample size was 10, 10, 6, 7, 9, and 9 for the six groups, respectively. *Mature rats were administered either "low" dose alcohol (75 mmol/kg) or "high" dose alcohol (90 mmol/kg); young rats were injected with 75 mmol/kg. The abundance of IGFBP-1, BP-2 and ALS was below the detection limit in muscle for all rats and data are not reported. Values with different letters for a particular hormone are significantly different from each other, P < 0.05. Values with the same letter are not significantly different.