Body weight change and caloric intake. Body weight (A) increased similarly in KD and CH over time until KD rats were switched to CH. After the switch, the KD:CH group had a significantly greater change in body weight. Mean weekly caloric intake was not different between dietary groups prior to the dietary switch (B). KD:CH rats demonstrated a transient decrease in caloric intake and subsequent hyperphagia, as compared to CH rats, for the final 3 weeks of the experiment. Data are represented as mean ± SEM. * denotes a statistically significant difference from CH values.