Per os administered refined olive oil and marine PUFA-rich oils reach the cornea: possible role on oxidative stress through caveolin-1 modulation

Table 2 Fatty acids composition (%) of corneal membranes

	Control	Refined Olive oil	Microalgae DHA oil	EPAX 1050 oil	EPAX 6000 oil
C18:1 w9 (oleic acid)	21.2 (0.22)	27.4 (0.68)***	23.1 (1.63)	23.0 (0.51)**	25.0 (0.46)*
C20:4 w6 (arachidonic acid)	13.8 (0.59)	9.4 (0.37)**	9.9 (2.05)	10.4 (0.58)*	10.5 (0.0)**
MUFA	30.9 (1.07)	39.1 (0.75)**	33.0 (2.59)	33.0 (0.93)	36.3 (0.22)*
PUFA	25 (0.78)	18.9 (0.4)**	22.0 (3.55)	21.3 (0.87)*	20.9 (0.44)*
Ratio w6-w3	6.0 (0.75)	7.3 (0.89)	2.5 (0.25)**	3.6 (0.35)**	4.7 (0.40)

MUFA: monounsaturated fatty acids, PUFA: polyunsaturated fatty acids
Rats were fed with oils during 28 days and after euthanasia, fatty acids of corneas were analysed using gas chromatography. * p < 0.01, **p < 0.005, ***p < 0.001 (according to Tukey's test).

ISSN: 1743-7075