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Table 1 Patient Characteristics.

From: Plasma PLTP activity is inversely associated with HDL-C levels

Characteristics†

PLTP* genotype (N)

p-value‡

 

gg (277)

gc(276)

cc(69)

 

Age (years)

61.3 ± 10.5

63.3 ± 9.9

63.0 ± 9.4

0.06

Gender

    

   Men (%)

211(76.2)

222(80.4)

54(78.3)

0.64

   Women (%)

65(23.5)

54(19.6)

15(21.7)

 

BMI§ (kg/m2)

24.7 ± 2.9

24.5 ± 2.9

24.5 ± 3.2

0.55

Diabetes (%)

56(20.21)

51(18.5)

11(15.9)

0.69

Hypertension (%)

171(61.7)

175(63.4)

23(33.3)

0.77

Smoking (%)

126(45.5)

133(48.2)

29(42.0)

0.61

CHD|| (%)

176(63.5)

189(68.4)

42(60.8)

0.33

PLTP activity (pmol/μl/h) €

23.7 ± 14.7

24.7 ± 14.0

26.7 ± 12.8

0.04

0.02 †† (cc vs gg)

0.26 †† (cc vs gc)

0.07 †† (gg vs gc)

Total-C¶ (mmol/L)

4.71 ± 0.96

4.41 ± 1.03

4.40 ± 0.99

0.74

TG# (mmol/L)

1.74 ± 0.87

1.71 ± 1.08

1.8 ± 0.99

0.79

LDL-C (mmol/L)

2.65 ± 0.85

2.60 ± 0.88

2.55 ± 0.89

0.67

HDL-C (mmol/L)

1.03 ± 0.26

1.04 ± 0.29

1.01 ± 0.27

0.94

Low HDL-C (<0.8 mmol/L) (%)

81(29.2)

80(29.0)

21(30.4)

0.94

LDL-C/HDL-C

2.74 ± 1.28

2.63 ± 0.99

2.71 ± 1.24

0.50

ApoA-I** (g/L)

1.07 ± 0.19

1.06 ± 0.21

1.03 ± 0.21

0.18

apoB (g/L)

0.82 ± 0.42

0.82 ± 0.42

0.79 ± 0.26

0.87

apoE (mg/L)

47.99 ± 25.57

47.34 ± 18.39

45.17 ± 13.00

0.63

Lp(a)€ (mg/L)

179.76 ± 157.41

202.89 ± 187.61

199.51 ± 227.73

0.30

  1. * PLTP = Phospholipid transfer protein; † Means are presented ± standard deviation; ‡ p-values for differences in means were calculated using t test statistics, p-values for differences in proportions were calculated using Pearson's X2 test, †† p-values for differences using an LSD test for multiple comparisons; § BMI = body mass index; || CHD = Coronary Heart Disease with ≥50% coronary artery stenosis; € compared after log10 transformation; ¶ Cholesterol; # Triglycerides; ** Apolipoprotein.