Skip to main content

Advertisement

Table 1 Patient Characteristics.

From: Plasma PLTP activity is inversely associated with HDL-C levels

Characteristics† PLTP* genotype (N) p-value‡
  gg (277) gc(276) cc(69)  
Age (years) 61.3 ± 10.5 63.3 ± 9.9 63.0 ± 9.4 0.06
Gender     
   Men (%) 211(76.2) 222(80.4) 54(78.3) 0.64
   Women (%) 65(23.5) 54(19.6) 15(21.7)  
BMI§ (kg/m2) 24.7 ± 2.9 24.5 ± 2.9 24.5 ± 3.2 0.55
Diabetes (%) 56(20.21) 51(18.5) 11(15.9) 0.69
Hypertension (%) 171(61.7) 175(63.4) 23(33.3) 0.77
Smoking (%) 126(45.5) 133(48.2) 29(42.0) 0.61
CHD|| (%) 176(63.5) 189(68.4) 42(60.8) 0.33
PLTP activity (pmol/μl/h) 23.7 ± 14.7 24.7 ± 14.0 26.7 ± 12.8 0.04 0.02 †† (cc vs gg) 0.26 †† (cc vs gc) 0.07 †† (gg vs gc)
Total-C (mmol/L) 4.71 ± 0.96 4.41 ± 1.03 4.40 ± 0.99 0.74
TG# (mmol/L) 1.74 ± 0.87 1.71 ± 1.08 1.8 ± 0.99 0.79
LDL-C (mmol/L) 2.65 ± 0.85 2.60 ± 0.88 2.55 ± 0.89 0.67
HDL-C (mmol/L) 1.03 ± 0.26 1.04 ± 0.29 1.01 ± 0.27 0.94
Low HDL-C (<0.8 mmol/L) (%) 81(29.2) 80(29.0) 21(30.4) 0.94
LDL-C/HDL-C 2.74 ± 1.28 2.63 ± 0.99 2.71 ± 1.24 0.50
ApoA-I** (g/L) 1.07 ± 0.19 1.06 ± 0.21 1.03 ± 0.21 0.18
apoB (g/L) 0.82 ± 0.42 0.82 ± 0.42 0.79 ± 0.26 0.87
apoE (mg/L) 47.99 ± 25.57 47.34 ± 18.39 45.17 ± 13.00 0.63
Lp(a) (mg/L) 179.76 ± 157.41 202.89 ± 187.61 199.51 ± 227.73 0.30
  1. * PLTP = Phospholipid transfer protein; † Means are presented ± standard deviation; ‡ p-values for differences in means were calculated using t test statistics, p-values for differences in proportions were calculated using Pearson's X2 test, †† p-values for differences using an LSD test for multiple comparisons; § BMI = body mass index; || CHD = Coronary Heart Disease with ≥50% coronary artery stenosis; € compared after log10 transformation; ¶ Cholesterol; # Triglycerides; ** Apolipoprotein.