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Table 4 Correlation of changes in serum ketone bodies, FFAs and triglycerides with insulin response capacity, background dietary %carbohydrate and increases in plasma glucose after intake of the high-carbohydrate meal

From: Acute metabolic responses to a high-carbohydrate meal in outpatients with type 2 diabetes treated with a low-carbohydrate diet: a crossover meal tolerance study

 

Δβ-hydroxybutyrate

Δacetoacetate

ΔFFAs

Δtriglyceride

Fasting plasma glucose

-0.261 (0.156)

-0.208 (0.26)

-0.208 (0.26)

0.001 (0.10)

Δglucose

-0.472 (0.007)

-0.442 (0.012)

-0.302 (0.10)

-0.250 (0.18)

AUC-glucose

-0.450 (0.011)

-0.407 (0.023)

-0.358 (0.048)

-0.149 (0.42)

Fasting serum insulin

0.279 (0.13)

0.145 (0.44)

-0.114 (0.54)

-0.146 (0.42)

Δinsulin

0.328 (0.072)

0.268 (0.15)

0.012 (0.95)

-0.097 (0.60)

AUC-insulin

0.346 (0.057)

0.265 (0.15)

-0.007 (0.97)

-0.165 (0.38)

Insulinogenic index

0.503 (0.004)

0.509 (0.003)

0.359 (0.047)

0.048 (0.80)

HOMA-R

0.195 (0.292)

-0.129 (0.488)

0.035 (0.85)

-0.238 (0.20)

%Carbohydrate

0.380 (0.035)

0.372 (0.040)

0.268 (0.145)

0.484 (0.006)

  1. Values indicate Spearman's r with P values in parentheses. FFAs: free fatty acids, AUC: area under curve.
  2. Δglucose and Δinsulin: level at the peak - level at baseline.
  3. Δβ-hydroxybutyrate, Δacetoacetate, Δfree fatty acids (ΔFFAs) and Δtriglyceride: level at 120 minutes - level at baseline.