A high protein moderate carbohydrate diet fed at discrete meals reduces early progression of N-methyl-N-nitrosourea-induced breast tumorigenesis in rats

Table 3 Plasma Metabolic Measurements

			Fasted	Fed	Time Effect P Value	Time × Diet Effect P Value
Glucose (mmol/L)	3 wk	LPHC	6.86 ± 0.50	6.74 ± 0.44	0.854	0.841
		HPMC	7.16 ± 0.48	6.84 ± 0.47	0.642
	10 wk	LPHC	6.73 ± 0.18	6.54 ± 0.27	0.565	0.656
		HPMC	6.70 ± 0.27	6.74 ± 0.31	0.917
Insulin (pmol/L)	3 wk	LPHC	77.4 ± 11.6	213.8 ± 33.1	0.003	0.075
		HPMC	125.1 ± 19.8	163.2 ± 23.4	0.350
	10 wk	LPHC	86.2 ± 10.4	194.4 ± 29.7	0.002	0.520
		HPMC	77.5 ± 5.8	220.2 ± 37.6	0.003
IGF-I (μg/L)	3 wk	LPHC	240 ± 24	272 ± 26	0.396	0.564
		HPMC	274 ± 10	268 ± 32	0.917
	10 wk	LPHC	205 ± 30	211 ± 17	0.851	0.221
		HPMC	237 ± 17	299 ± 23	0.055

ISSN: 1743-7075