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Table 4 Systolic and diastolic blood pressure (BP) of the rats in the absence of salt-loading

From: Dietary phytosterols and phytostanols decrease cholesterol levels but increase blood pressure in WKY inbred rats in the absence of salt-loading

 

Control diet (n = 10)

Phytosterol diet (n = 10)

Phytostanol diet (n = 10)

P value (one-way ANOVA)

Initial systolic BP (mmHg)

113.7 ± 7.3

110.9 ± 10.7

115.3 ± 8.8

0.5857

Systolic BP at week 5 (mmHg)

127.0 ± 6.2a#

136.0 ± 8.2b#

138.6 ± 7.4b#

0.0067

Change in systolic BP (mmHg/5 weeks)

13.3 ± 8.5a

25.1 ± 12.0b

23.4 ± 9.1b

0.0333

Initial diastolic BP (mmHg)

78.0 ± 3.9

81.0 ± 7.8

79.9 ± 6.1

0.5373

Diastolic BP at week 5 (mmHg)

82.6 ± 4.0a#

89.7 ± 5.8b#

95.2 ± 5.8c#

0.0001

Change in diastolic BP (mmHg/5 weeks)

4.6 ± 3.6a

8.7 ± 5.8b

15.2 ± 7.1c

0.0021

  1. Values are presented as means ± SD.
  2. a,b,c means in a row not sharing a superscript letter are significantly different (P < 0.05, Duncan's test).
  3. # means significantly different from initial measurement of systolic or diastolic blood pressure, respectively (week 5 vs initial, P < 0.05, t-test).