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Table 2 Serum Uric Acid Concentrations by Dietary Fructose, Alcohol, and Fiber Intakes [mean (SD), mg/dL], in Adult Population, Age 20-80 y, NHANES 1999-2004*

From: Lack of association between dietary fructose and hyperuricemia risk in adults

N = 9,384

By fructose intake quartiles

 
 

1

2

3

4

P of model

Added unbound fructose (g/d)

(≤ 3.84)

(≤ 14.63)

(≤ 30.04)

(>30.04)

 

   Unadjusted model

5.25 (1.48)

5.10 (1.41)b

5.23 (1.39)

5.44 (1.42)c

< 0.0001

   Adjusted model

5.58 (1.56)

5.50 (1.57)a

5.58 (1.59)

5.63 (1.81)

0.004

All added fructose (g/d)

(≤ 15.98)

(≤ 31.60)

(≤ 54.43)

(>54.43)

 

   Unadjusted model

5.23 (1.46)

5.19 (1.43)

5.18 (1.43)

5.40 (1.40)c

0.0002

   Adjusted model

5.57 (1.60)

5.57 (1.55)

5.54 (1.64)

5.59 (1.91)

0.531

Total fructose (g/d)

(≤ 24.29)

(≤ 41.23)

(≤ 64.11)

(>64.11)

 

   Unadjusted model

5.29 (1.49)

5.21 (1.42)

5.16 (1.41)b

5.36 (1.40)

0.01

   Adjusted model

5.62 (1.62)

5.56 (1.56)

5.53 (1.65)

5.54 (1.94)

0.158

Added unbound fructose (% kcal)

(≤ 0.78)

(≤ 2.73)

(≤ 5.50)

(>5.50)

 

   Unadjusted model

5.28 (1.48)

5.13 (1.41)b

5.27 (1.40)

5.33 (1.42)

0.002

   Adjusted model

5.58 (1.53)

5.49 (1.57)a

5.59 (1.60)

5.64 (1.76)

0.006

Added all fructose (% kcal)

(≤ 3.57)

(≤ 6.36)

(≤ 9.68)

(>9.68)

 

   Unadjusted model

5.35 (1.49)

5.19 (1.43)c

5.21 (1.40)b

5.26 (1.41)

0.001

   Adjusted model

5.58 (1.54)

5.55 (1.54)

5.55 (1.56)

5.62 (1.84)

0.174

Total fructose (% kcal)

(≤ 5.48)

(≤ 8.28)

(≤ 11.48)

(>11.48)

 

   Unadjusted model

5.42 (1.50)

5.25 (1.39)c

5.14 (1.42)c

5.2 (1.41)c

< 0.0001

   Adjusted model

5.58 (1.53)

5.57 (1.56)

5.53 (1.63)

5.62 (1.85)

0.098

N = 9,384

By alcohol intake levels (g/day)

 
 

1 (0)

2 (≤ 15)

3 (≤ 30)

4 (>30)

 

   Unadjusted model

5.12 (1.41)

5.17 (1.40)

5.73 (1.42)c

5.93 (1.39)c

< 0.0001

   Adjusted model

5.31 (1.87)

5.38 (1.27)

5.65 (1.22)c

5.72 (1.39)c

< 0.0001

N = 9,384

By fiber intake quartiles (g/1000 kcal, 1 kcal = 4.184 kJ)

 
 

1 (≤ 4.6)

2 (≤ 6.7)

3 (≤ 9.5)

4 (>9.5)

 

   Unadjusted model

5.49 (1.50)

5.26 (1.43)c

5.18 (1.41)c

5.08 (1.36)c

< 0.0001

   Adjusted model

5.60 (1.33)

5.51 (1.16)a

5.51 (1.50)a

5.45 (1.34)c

0.0016

  1. *Serum uric acid 1 mg/dL = 59.48 μmol/L. Compared to the values of intake level 1 or quartile1, superscripted letter a represents P < 0.05, b represents P < 0.01, and c represents P < 0.001.
  2. Adjusted model = adjusted for sex, age, BMI, race, education, quartile intakes of kcal, protein, total fat, total fructose (in modeling alcohol/fiber intakes), fiber/1000 kcal, and vitamin C, and alcohol intake level.