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Table 3 Influence of Fructose, Alcohol, and Fiber Intakes on the Risk of Hyperuricemia in Adult Population Aged 20-80 y, NHANES 1999-2004, Odds Ratios (95% confidence limits)*

From: Lack of association between dietary fructose and hyperuricemia risk in adults

N = 9,384

Fructose intake quartiles

 
 

1

2

3

4

P of model

Added unbound fructose (g/d)

(≤ 3.84)

(≤ 14.63)

(≤ 30.04)

(>30.04)

 

   Unadjusted model

1

0.625 (0.435-0.899)a

0.717 (0.506-1.016)

0.758 (0.537-1.069)

0.061

   Adjusted model

1

0.731 (0.501-1.066)

0.815 (0.554-1.197)

0.916 (0.586-1.431)

0.381

All added fructose (g/d)

(≤ 15.98)

(≤ 31.60)

(≤ 54.43)

(>54.43)

 

   Unadjusted model

1

0.823 (0.583-1.163)

0.716 (0.501-1.025)

0.728 (0.51-1.04)

0.215

   Adjusted model

1

0.952 (0.659-1.375)

0.896 (0.589-1.363)

0.992 (0.598-1.645)

0.944

Total fructose (g/d)

(≤ 24.29)

(≤ 41.23)

(≤ 64.11)

(>64.11)

 

   Unadjusted model

1

0.642 (0.457-0.901)a

0.576 (0.405-0.817)b

0.515 (0.359-0.74)c

0.001

   Adjusted model

1

0.694 (0.481-1.001)

0.697 (0.458-1.06)

0.603 (0.357-1.019)

0.154

Added unbound fructose (% kcal)

(≤ 0.78)

(≤ 2.73)

(≤ 5.50)

(>5.50)

 

   Unadjusted model

1

0.622 (0.432-0.897)a

0.727 (0.512-1.032)

0.807 (0.573-1.136)

0.068

   Adjusted model

1

0.736 (0.504-1.075)

0.831 (0.567-1.217)

0.854 (0.564-1.293)

0.456

Added all fructose (% kcal)

(≤ 3.57)

(≤ 6.36)

(≤ 9.68)

(>9.68)

 

   Unadjusted model

1

0.663 (0.464-0.947)

0.734 (0.518-1.039)

0.716 (0.504-1.016)

0.088

   Adjusted model

1

0.785 (0.54-1.14)

0.868 (0.59-1.275)

0.766 (0.489-1.2)

0.549

Total fructose (% kcal)

(≤ 5.48)

(≤ 8.28)

(≤ 11.48)

(>11.48)

 

   Unadjusted model

1

0.644 (0.453-0.915)a

0.698 (0.495-0.984)a

0.617 (0.432-0.882)b

0.02

   Adjusted model

1

0.754 (0.521-1.091)

0.853 (0.578-1.259)

0.715 (0.453-1.128)

0.374

N = 9384

Alcohol intake levels (g/d)

 
 

1 (0)

2 (≤ 15)

3 (≤ 30)

4 (>30)

 

   Unadjusted model

1

0.787 (0.475-1.304)

1.729 (1.076-2.777)a

1.829 (1.309-2.556)c

< 0.001

   Adjusted model

1

0.86 (0.513-1.443)

1.511 (0.912-2.505)

1.658 (1.078-2.549)a

0.057

N = 9384

Fiber intake quartiles (g/1000 kcal, 1 kcal = 4.184 kJ)

 
 

1 (≤ 4.6)

2 (≤ 6.7)

3 (≤ 9.5)

4 (>9.5)

 

   Unadjusted model

1

0.599 (0.427-0.839)b

0.522 (0.367-0.742)c

0.478 (0.333-0.686)c

< 0.001

   Adjusted model

1

0.637 (0.445-0.912)a

0.552 (0.373-0.816)b

0.448 (0.291-0.69)c

0.0013

  1. *Compared to the values of intake quartile1 or level 1, superscripted letter a represents P < 0.05, b represents P < 0.01, and c represents P < 0.001.
  2. Adjusted model = adjusted for sex, age, BMI, race, education, quartile intakes of kcal, protein, total fat, total fructose (in modeling alcohol/fiber intakes), fiber/1000 kcal, and vitamin C, and alcohol intake level.
  3. The range of P values for tests of model Goodness of Fit was between 0.17-0.87, which indicates that dependent variable could be satisfactorily explained by independent variables.