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Figure 3 | Nutrition & Metabolism

Figure 3

From: Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats

Figure 3

Urinary phenolsulfonphthalein (PSP, A) and Cr-EDTA (B and C) excretion for 48 h after administration of their oral loads in the OLETF and LETO rats fed the standard and high fat diets. The intestinal permeability tests were performed at 3 (A), 9 (B), and 15 (C) weeks after the start of feeding the experimental diets. Each value represents mean ± SEM, n = 9. Means without a common letter differ, P < 0.05. P values estimated by 2 way ANOVA were (A) 0.24 for strain, < 0.01 for diet, and 0.67 for strain × diet, (B) 0.04 for strain, < 0.01 for diet, and 0.79 for strain × diet, and (C) 0.79 for strain, <0.01 for diet, and 0.16 for strain × diet.

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