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Figure 8 | Nutrition & Metabolism

Figure 8

From: Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats

Figure 8

Transepithelial electrical resistance (TER) and lucifer yellow (LY) flux across the Caco-2 cell monolayers incubated with or without rat bile juice (2.5-20 %, A and B) and fat emulsion (0.1-1.0%, C and D) for 72 h. TER (A and C) was measured at 0, 24, 48, and 72 h after the start of incubation. LY flux (B and D) was measured for 3 h to 48 h. Each value represents mean ± SEM, n = 6. Means without a common letter differ, P < 0.05. P values estimated by repeated measure 1 way ANOVA or 1 way ANOVA were (A) < 0.01 for time, < 0.01 for treatment, and < 0.01 for time × treatment, (B) < 0.01, (C) 0< 0.01 for time, < 0.01 for treatment, and < 0.01 for time × treatment, and (D) < 0.01.

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Nutrition & Metabolism

ISSN: 1743-7075

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