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Table 1 Anthropometric and biochemical characteristics of studied subjects.

From: Study of caveolin-1 gene expression in whole adipose tissue and its subfractions and during differentiation of human adipocytes

 

Non-obese

Obese

Morbidly Obese

p

N

39

17

34

 

Sex (M/F)

15/24

6/11

10/24

0.72

Body Mass Index (kg/m 2 )

25.4 ± 3.5

35.3 ± 3.1

46.1 ± 5.5

< 0.0001

Age (years)

46.7 ± 13.7

53.1 ± 14.9

43.1 ± 11

0.03

Glucose (mg/dl)

93.8 ± 32.2

91.25 ± 11.8

124.8 ± 59.4

0.005

Cholesterol (mg/dl)

195.5 ± 41.5

182.2 ± 34.8

189 ± 31.6

0.47

LDL-cholesterol (mg/dl)

118 ± 35.8

99.6 ± 32.1

110.8 ± 36.7

0.27

HDL-cholesterol (mg/dl)

57.2 ± 16.7

54.5 ± 16.9

59.15 ± 58.7

0.93

Log fasting tryglicerides

1.98 ± 0.2

2.03 ± 0.2

2.11 ± 0.2

0.08

ACACA visceral (RU)

0.04 ± 0.01

0.017 ± 0.003

0.02 ± 0.001

0.001

ACACA subcutaneous (RU)*

0.033 ± 0.006

0.015 ± 0.002

0.02 ± 0.002

0.03

FASN visceral (RU)

0.16 ± 0.02

0.07 ± 0.01

0.09 ± 0.01

0.02

FASN subcutaneous (RU)*

0.36 ± 0.14

0.07 ± 0.02

0.06 ± 0.009

0.01

SREBP-1c visceral (RU)

0.018 ± 0.002

0.013 ± 0.001

0.014 ± 0.001

0.2

SREBP-1c subcutaneous (RU)*

0.019 ± 0.004

0.009 ± 0.001

0.009 ± 0.001

0.04

Spot-14 visceral (RU)

0.26 ± 0.03

0.26 ± 0.03

0.23 ± 0.01

0.6

Spot-14 subcutaneous (RU)*

0.60 ± 0.05

0.45 ± 0.003

0.48 ± 0.03

0.04

Caveolin visceral (RU)

1.68 ± 0.9

1.04 ± 0.3

1.05 ± 0.3

< 0.0001

Caveolin subcutaneous (RU)*

1.50 ± 0.4

1.78 ± 0.8

1.44 ± 0.4

0.22

  1. ACACA, acetyl coA carboxylase; FAS, fatty acid synthase; SREBP-1c, sterol-regulatory-element-binding protein; RU, relative units. Values are expressed as mean ± SD except for gene expressions that are expressed as mean ± SEM.
  2. *Subcutaneous adipose samples were studied in 16 non-obese, 13 obese and 26 morbidly obese subjects.