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Table 1 Anthropometric and biochemical characteristics of studied subjects.

From: Study of caveolin-1 gene expression in whole adipose tissue and its subfractions and during differentiation of human adipocytes

  Non-obese Obese Morbidly Obese p
N 39 17 34  
Sex (M/F) 15/24 6/11 10/24 0.72
Body Mass Index (kg/m 2 ) 25.4 ± 3.5 35.3 ± 3.1 46.1 ± 5.5 < 0.0001
Age (years) 46.7 ± 13.7 53.1 ± 14.9 43.1 ± 11 0.03
Glucose (mg/dl) 93.8 ± 32.2 91.25 ± 11.8 124.8 ± 59.4 0.005
Cholesterol (mg/dl) 195.5 ± 41.5 182.2 ± 34.8 189 ± 31.6 0.47
LDL-cholesterol (mg/dl) 118 ± 35.8 99.6 ± 32.1 110.8 ± 36.7 0.27
HDL-cholesterol (mg/dl) 57.2 ± 16.7 54.5 ± 16.9 59.15 ± 58.7 0.93
Log fasting tryglicerides 1.98 ± 0.2 2.03 ± 0.2 2.11 ± 0.2 0.08
ACACA visceral (RU) 0.04 ± 0.01 0.017 ± 0.003 0.02 ± 0.001 0.001
ACACA subcutaneous (RU)* 0.033 ± 0.006 0.015 ± 0.002 0.02 ± 0.002 0.03
FASN visceral (RU) 0.16 ± 0.02 0.07 ± 0.01 0.09 ± 0.01 0.02
FASN subcutaneous (RU)* 0.36 ± 0.14 0.07 ± 0.02 0.06 ± 0.009 0.01
SREBP-1c visceral (RU) 0.018 ± 0.002 0.013 ± 0.001 0.014 ± 0.001 0.2
SREBP-1c subcutaneous (RU)* 0.019 ± 0.004 0.009 ± 0.001 0.009 ± 0.001 0.04
Spot-14 visceral (RU) 0.26 ± 0.03 0.26 ± 0.03 0.23 ± 0.01 0.6
Spot-14 subcutaneous (RU)* 0.60 ± 0.05 0.45 ± 0.003 0.48 ± 0.03 0.04
Caveolin visceral (RU) 1.68 ± 0.9 1.04 ± 0.3 1.05 ± 0.3 < 0.0001
Caveolin subcutaneous (RU)* 1.50 ± 0.4 1.78 ± 0.8 1.44 ± 0.4 0.22
  1. ACACA, acetyl coA carboxylase; FAS, fatty acid synthase; SREBP-1c, sterol-regulatory-element-binding protein; RU, relative units. Values are expressed as mean ± SD except for gene expressions that are expressed as mean ± SEM.
  2. *Subcutaneous adipose samples were studied in 16 non-obese, 13 obese and 26 morbidly obese subjects.