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Table 6 Food and water intake, body and organ weights, blood glucose and plasma lipids for 20-wk old Nile rats fed chow #5020 ad libitum or restricted to 75% ad libitum for 18 wks (Expt 8)

From: Nutritional correlates and dynamics of diabetes in the Nile rat (Arvicanthis niloticus): a novel model for diet-induced type 2 diabetes and the metabolic syndrome

  Chow 5020
  ad libitum Restricted to 75%
CHO:FAT:Prot %en 57:21:22 57:21:22
Diet: Kcal/g 3.75 3.75
Body weight (g)   
   Initial (age: 20 wks) 112 ± 20 102 ± 8
   Final after 13 wks 119 ± 23 110 ± 9
   Final after 18 wks 123 ± 21 112 ± 15
   gain/day 0.019 ± 0.007 0.020 ± 0.024
Food intake (g/d) 17.4 ± 6.8 13.0 ± 3.0
   (kcal/d) 65 ± 25 49 ± 11
Water intake (ml/d) 19.9 ± 15.0 20.7 ± 14.4
Organ weight (%BW)   
   Liver 4.36 ± 0.98 3.40 ± 0.36*
   Kidneys 1.01 ± 0.24 0.89 ± 0.17
   Cecum 1.86 ± 0.5 1.61 ± 0.28
   Adipose   
Perirenal 1.21 ± 0.54 0.91 ± 0.70
Epididymal 2.26 ± 1.06 2.35 ± 0.70
Inguinal 1.45 ± 0.39 1.15 ± 0.23
Omental 1.09 ± 0.16 0.88 ± 0.29
Suprascapular (brown fat) 3.01 ± 1.18 1.80 ± 0.74
Total (all above) 9.03 ± 2.21 7.10 ± 2.05
   Carcass 68.5 ± 2.86 70.0 ± 3.71
Body Length 13.7 ± 0.9 13.5 ± 0.4
BMI (kg/m2) 6.5 ± 0.3 6.2 ± 0.5
LMI (kg/m2) 4.4 ± 0.3 4.3 ± 0.3
ipGTT at 18 wk   
0 time 211 ± 152 72 ± 35*
1 hr 517 ± 172 226 ± 135*
Blood glucose (15 h fasting), mg/dL   
   Initial 56 ± 19 60 ± 41
   After 13 wks 70 ± 21 36 ± 3*
   Final after 18 wks 211 ± 152 72 ± 35*
Plasma lipids (terminal)   
   TC (mg/dL) 169 ± 68 115 ± 22
   TG (mg/dL) 179 ± 149 56 ± 19
  1. Values are Mean ± SD, (n = 5-6; 2-3 females and 2-4 males per group)
  2. * Significanly different (p < 0.05)