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Table 1 Anthropometrical and biochemical characteristics of study subjects: normal, overweight and obese individuals

From: Inverse relation between FASN expression in human adipose tissue and the insulin resistance level

  

Means

SD

P

  

Means

SD

P

BMI

Normal

22.453

2.317

0.00

TG

Normal

83.353

32.017

0.00

 

Overweight

27.389

1.563

  

Overweight

141.600

81.945

 
 

Obese

34.393

3.801

  

Obese

141.286

63.364

 
 

Total

26.554

4.856

  

Total

117.687

68.273

 

SBP

Normal

121.543

20.860

0.00

LDL-c

Normal

123.294

28.510

0.88

 

Overweight

131.114

15.854

  

Overweight

122.229

28.823

 
 

Obese

140.857

17.110

  

Obese

126.857

26.921

 
 

Total

128.750

19.392

  

Total

123.446

28.091

 

DBP

Normal

75.086

12.344

0.25

HDL-c

Normal

55.853

15.182

0.30

 

Overweight

76.857

10.097

  

Overweight

51.800

12.211

 
 

Obese

80.714

6.390

  

Obese

50.286

9.659

 
 

Total

76.762

10.696

  

Total

53.205

13.213

 

W-H ratio

Normal

0.862

0.080

0.02

CRP

Normal

5.285

17.498

0.16

 

Overweight

0.897

0.068

  

Overweight

3.254

2.576

 
 

Obese

0.930

0.093

  

Obese

11.143

14.854

 
 

Total

0.888

0.081

  

Total

5.417

12.983

 

Insulin

Normal

10.824

6.162

0.11

Adiponectin

Normal

23.423

14.405

0.00

 

Overweight

13.537

6.134

  

Overweight

13.794

5.904

 
 

Obese

14.736

7.938

  

Obese

16.963

6.891

 
 

Total

12.685

6.593

  

Total

18.190

11.087

 

Glycaemia

Normal

79.735

8.972

0.01

Leptin

Normal

12.005

14.011

0.00

 

Overweight

100.200

37.802

  

Overweight

18.745

16.660

 
 

Obese

93.857

11.455

  

Obese

33.039

22.406

 
 

Total

90.747

27.125

  

Total

18.730

18.300

 

HbA1c

Normal

5.509

0.330

0.00

FASN

Normal

0.316

0.179

0.00

 

Overweight

5.829

0.688

  

Overweight

0.194

0.151

 
 

Obese

6.064

0.472

  

Obese

0.127

0.100

 
 

Total

5.737

0.565

  

Total

0.237

0.172

 

HOMA-IR

Normal

2.129

1.103

0.00

PPARγ1

Normal

0.031

0.048

0.39

 

Overweight

3.373

1.911

  

Overweight

0.086

0.232

 
 

Obese

3.639

2.201

  

Obese

0.100

0.267

 
 

Total

2.914

1.787

  

Total

0.063

0.181

 

Cholesterol

Normal

199.529

39.368

0.96

PPARγ2

Normal

0.006

0.004

0.36

 

Overweight

200.543

36.575

  

Overweight

0.007

0.005

 
 

Obese

202.786

33.971

  

Obese

0.005

0.003

 
 

Total

200.506

36.914

  

Total

0.007

0.004

 
  1. Values are presented as means ± SD. BMI, body mass index (Kg/m2); SBP, systolic blood pressure (mm Hg); DBP, diastolic blood pressure (mm Hg); W-H ratio, waist to hip ratio; Insulin (UI/ml); Glycaemia (mg/dl); HbA1c, glycated haemoglobin (%); HOMA-IR, homeostasis model assessment ((gluc mg/dl*insul U/ml)/405); Cholesterol (mg/dl); TG, triglycerides (mg/dl); LDL-c, low density lipoprotein-cholesterol (mg/dl); HDL-c, high density lipoprotein-cholesterol (mg/dl); CRP, c-reactive protein (mg/l); Adiponectin (ng/ml); Leptin (ng/ml); FASN, fatty acid synthase; PPARγ, peroxisome proliferator-activated receptor.