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Table 1 Anthropometrical and biochemical characteristics of study subjects: normal, overweight and obese individuals

From: Inverse relation between FASN expression in human adipose tissue and the insulin resistance level

   Means SD P    Means SD P
BMI Normal 22.453 2.317 0.00 TG Normal 83.353 32.017 0.00
  Overweight 27.389 1.563    Overweight 141.600 81.945  
  Obese 34.393 3.801    Obese 141.286 63.364  
  Total 26.554 4.856    Total 117.687 68.273  
SBP Normal 121.543 20.860 0.00 LDL-c Normal 123.294 28.510 0.88
  Overweight 131.114 15.854    Overweight 122.229 28.823  
  Obese 140.857 17.110    Obese 126.857 26.921  
  Total 128.750 19.392    Total 123.446 28.091  
DBP Normal 75.086 12.344 0.25 HDL-c Normal 55.853 15.182 0.30
  Overweight 76.857 10.097    Overweight 51.800 12.211  
  Obese 80.714 6.390    Obese 50.286 9.659  
  Total 76.762 10.696    Total 53.205 13.213  
W-H ratio Normal 0.862 0.080 0.02 CRP Normal 5.285 17.498 0.16
  Overweight 0.897 0.068    Overweight 3.254 2.576  
  Obese 0.930 0.093    Obese 11.143 14.854  
  Total 0.888 0.081    Total 5.417 12.983  
Insulin Normal 10.824 6.162 0.11 Adiponectin Normal 23.423 14.405 0.00
  Overweight 13.537 6.134    Overweight 13.794 5.904  
  Obese 14.736 7.938    Obese 16.963 6.891  
  Total 12.685 6.593    Total 18.190 11.087  
Glycaemia Normal 79.735 8.972 0.01 Leptin Normal 12.005 14.011 0.00
  Overweight 100.200 37.802    Overweight 18.745 16.660  
  Obese 93.857 11.455    Obese 33.039 22.406  
  Total 90.747 27.125    Total 18.730 18.300  
HbA1c Normal 5.509 0.330 0.00 FASN Normal 0.316 0.179 0.00
  Overweight 5.829 0.688    Overweight 0.194 0.151  
  Obese 6.064 0.472    Obese 0.127 0.100  
  Total 5.737 0.565    Total 0.237 0.172  
HOMA-IR Normal 2.129 1.103 0.00 PPARγ1 Normal 0.031 0.048 0.39
  Overweight 3.373 1.911    Overweight 0.086 0.232  
  Obese 3.639 2.201    Obese 0.100 0.267  
  Total 2.914 1.787    Total 0.063 0.181  
Cholesterol Normal 199.529 39.368 0.96 PPARγ2 Normal 0.006 0.004 0.36
  Overweight 200.543 36.575    Overweight 0.007 0.005  
  Obese 202.786 33.971    Obese 0.005 0.003  
  Total 200.506 36.914    Total 0.007 0.004  
  1. Values are presented as means ± SD. BMI, body mass index (Kg/m2); SBP, systolic blood pressure (mm Hg); DBP, diastolic blood pressure (mm Hg); W-H ratio, waist to hip ratio; Insulin (UI/ml); Glycaemia (mg/dl); HbA1c, glycated haemoglobin (%); HOMA-IR, homeostasis model assessment ((gluc mg/dl*insul U/ml)/405); Cholesterol (mg/dl); TG, triglycerides (mg/dl); LDL-c, low density lipoprotein-cholesterol (mg/dl); HDL-c, high density lipoprotein-cholesterol (mg/dl); CRP, c-reactive protein (mg/l); Adiponectin (ng/ml); Leptin (ng/ml); FASN, fatty acid synthase; PPARγ, peroxisome proliferator-activated receptor.