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Table 1 Characteristics of the study groups.

From: Association of macrophage inhibitory cytokine-1 with nutritional status, body composition and bone mineral density in patients with anorexia nervosa: the influence of partial realimentation

  Controls
(n = 25)
AN pre-treatment
(n = 16)
AN post-treatment
(n = 16)
Age (years) 22.9 ± 0.50 24.9 ± 1.34 24.9 ± 1.34
Body mass index (kg/m2) 21.8 ± 0.38 15.7 ± 0.30* 17.5 ± 0.23*+
Body fat content (bodystat) (%) 21.9 ± 1.21 9.3 ± 1.65* 12.8 ± 1.38*+
Body fat content (DEXA) (%) 26.4 ± 1.79 13.9 ± 1.44* 18.0 ± 1.38*+
Lean body mass (kg) 52.5 ± 2.03 38.9 ± 1.3* 41.3 ± 0.96*
Resting energy expenditure (kcal/day) 1400.1 ± 35.92 1060.0 ± 40.25* 1176.3 ± 25.05*+
Fasting glucose (mmol/l) 4.4 ± 0.07 3.9 ± 0.09* 4.2 ± 0.08+
Total cholesterol (mmol/l) 4.2 ± 0.14 4.6 ± 0.26 5.2 ± 0.27*+
HDL-cholesterol (mmol/l) 1.6 ± 0.08 1.5 ± 0.10 1.6 ± 0.08
LDL-cholesterol (mmol/l) 2.1 ± 0.09 2.4 ± 0.18 3.0 ± 0.21*+
Free fatty acids (mmol/l) 0.64 ± 0.06 0.16 ± 0.02* Not measured
Total serum protein (g/l) 79.1 ± 1.49 68.7 ± 2.01* 75.5 ± 1.04+
Albumin (g/l) 46.4 ± 1.22 43.8 ± 1.12 47.6 ± 0.72+
Total bone mineral density (g/cm2) 1.09 ± 0.02 1.04 ± 0.02* Not measured
Lumbar (L1-L4) bone mineral density (g/cm2) 1.03 ± 0.03 0.86 ± 0.03* Not measured
Proximal femur bone mineral density (g/cm2) 0.98 ± 0.02 0.78 ± 0.04* Not measured
IGF-1 (ng/ml) NA 156 ± 18 NA
MIC-1 (pg/ml) 1051 ± 83 1872 ± 200* 1530 ± 169* +
Leptin (ng/ml) 11.8 ± 1.78 0.97 ± 0.23* 2.6 ± 0.66*+
  1. Anthropometric, hormonal and biochemical characteristics of the control group of normal-weight healthy women and patients with anorexia nervosa both before (AN pre-treatment) and after (AN post-treatment) treatment. Values are means ± SEM. Statistical significance is from unpaired t-test or Mann-Whitney test (AN vs. controls) and from paired t-test or Wilcoxon Signed Rank Test (post- vs. pre-treatment values in AN) as appropriate. *p < 0.05 vs. controls; +p < 0.05 vs. pre-treatment values. NA - not available