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Table 1 Serum concentrations of phytoestrogens

From: Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats

Treatment 4th week 10th week Reported rat serum concentrations (ng/ml)
DES 20 ± 5 ng/ml 353 ± 60 ng/ml For comparison, serum E2 levels in cycling
  (0.07 ± 0.02 μM) (1.3 ± 0.2 μM) F344 rats is 1-16 pg/ml (4-59 pM) [54]
Coumesterol 182 ± 18 ng/ml 590 ± 83 ng/ml ND-10 ng/ml (0.04 μM) [52]
  (0.68 ± 0.07 μM) (2.2 ± 0.31 μM)  
Daidzein 30 ± 2 ng/ml 43 ± 5 ng/ml ND-13 ng/ml (0.05 μM) [52]
  (0.12 ± 0.07 μM) (0.17 ± 0.02 μM)  
Genistein 14 ± 5 ng/ml 117 ± 12 ng/ml ND-28 ng/ml (0.10 μM) [52]
  (0.05 ± 0.02 μM) (0.43 ± 0.04 μM)  
T rans-resveratrol 58 ± 15 ng/ml 49 ± 9 ng/ml ND [27, 55]
  (0.25 ± 0.06 μM) (0.21 ± 0.04 μM)  
  1. Free phytoestrogens in blood from animals with implants for 4 or 10 weeks (n = 10 animals per group) are shown in both ng/ml and molar concentrations. Five blood samples from each group were analyzed. The control animals (with cholesterol implants) had below detectable levels for all measured compounds. The last column lists referenced phytoestrogen levels in rat serum from untreated rats. ND = nondetectable.