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Table 2 Combinations of DES and phytoestrogens increase the % of cells that have large nuclear size.

From: Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats

Treatment

% cells > 800

Without DES

% cells > 800

With DES

Cholesterol

1.67

3.71

Coumesterol

1.97

8.94

Daidzein

0.80

30.17

Genistein

0.24

16.35

Trans-resveratrol

3.13

23.49

  1. The percent of cells with nuclei areas above the 800 value for ranked nuclear size (see Figure. 7) is shown.