Figure 3
From: Vaticanol C, a resveratrol tetramer, activates PPARα and PPARβ/δ in vitro and in vivo
Induction of PPAR-dependent Genes by Vaticanol C and Fenofibrate. (A) mRNA levels of the indicated genes were measured by RT-qPCR in liver and skeletal muscle from WT (open column) and PPARα-knockout (closed column) mice fed a HF diet containing 60% energy as fat, supplemented with vaticanol C (0 and 0.04%) for 8 weeks. Results are presented as means ± S.D. (n = 4~7). * compared with the value of 0% vaticanol C (*, P < 0.05, **, P < 0.01). # compared with the value of the corresponding wild-type mice (#, p < 0.05, ##, p < 0.01).(B) mRNA levels of the indicated genes were measured by RT-qPCR in liver from WT fed a HF diet containing 60% energy as fat, supplemented with fenofibrate (0 and 0.02%) for 4 weeks. Results are presented as means ± S.D. (n = 4). * compared with the value of 0% fenofibrate (*, P < 0.05, **, P < 0.01).