Effects of CLA on body weight gain in mice. Mice received a daily dose of CLA equivalent to 3 mg CLA/animal in CLA1 group and 10 mg/animal in CLA2 group for the first 30 d and 6 mg CLA/animal in CLA1 group and 20 mg/animal in CLA2 group for the last 35 d of treatment. Data are means ± SEM of 8 mice. Repeated-measures analysis of variance of body weight gain associated with CLA treatment was significant with respect to the control (P < 0.05). No differences between doses were found. x2dose: indicates the point from which the double dose was given.