Table 3 Effects of CLA treatment on plasma concentration of metabolites in mice

30 days of treatment

   Glucose (mmol/L)

8.2 ± 0.2

7.6 ± 0.2

8.0 ± 0.3

   Adiponectin (μg/ml)

13.41 ± 1.35

13.78 ± 0.67

13.64 ± 1.14

   Leptin (ng/ml)

3.11 ± 0.88

2.08 ± 0.35

1.62 ± 0.27

65 days of treatment

   Glucose (mmol/L)

4.33 ± 0.23^ab

4.15 ± 0.14^a

4.90 ± 0.21^b

   Adiponectin (μg/ml)

17.33 ± 1.05^a

16.87 ± 0.84^a

11.64 ± 1.25^b

   Leptin (ng/ml)

2.09 ± 0.39^a

2.57 ± 0.45^a

0.45 ± 0.10^b

   Resistin (ng/ml)

15.27 ± 1.04

15.90 ± 0.91

14.32 ± 0.93

   NEFAs (mg/dl)

26.00 ± 1.80^a

19.36 ± 1.96^b

14.44 ± 1.47^b

   Glycerol (mg/ml)

0.19 ± 0.02^a

0.15 ± 0.02^a

0.06 ± 0.02^b

   Triglycerides (mg/ml)

0.61 ± 0.03

0.60 ± 0.05

0.51 ± 0.08

   Insulin (pmol/L)

15.95 ± 0.35^a

18.50 ± 0.87^b

19.89 ± 0.80^b

   Leptin/adiponectin ratio

0.12 ± 0.02^a

0.16 ± 0.03^a

0.04 ± 0.01^b

   HOMA-IR

0.42 ± 0.02^a

0.47 ± 0.02^a

0.60 ± 0.04^b

   R-QUICKI

0.46 ± 0.01

0.48 ± 0.01

0.49 ± 0.01