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Table 2 Uptake and relative distribution percentages of astaxanthin in whole leukocytes and subcellular fractions in cats fed 0, 0.02, 0.08, 0.4, 2, 5 or 10 mg astaxanthin daily for 15d

From: Astaxanthin uptake in domestic dogs and cats

 

Treatment (mg astaxanthin/cat/d)

 

0

0.02

0.08

0.4

2

5

10

Day 6

       

Whole leukocyte (nmol astaxanthin/108 cells)

 

nd

nd

nd

52 ± 0*

222 ± 76*

339 ± 75*

687 ± 29*

Subcellular fraction (% of whole leukocyte)

   Nuclei

nd

nd

nd

40

40

28

23

   Mitochondria

nd

nd

nd

60

41

44

50

   Microsome

nd

nd

nd

nd

19

14

14

   Cytosol

nd

nd

nd

nd

nd

14

13

Day 15

       

Whole leukocyte (nmol astaxanthin/108 cells)

 

nd

44 ± 0*

49 ± 0*

84 ± 3*

169 ± 33*

357 ± 56*

468 ± 36*

Subcellular fraction (% of whole leukocyte)

   Nuclei

nd

nd

nd

36

21

24

17

   Mitochondria

nd

nd

39

33

40

45

49

   Microsome

nd

46

31

16

20

15

18

   Cytosol

nd

54

30

16

20

16

15

  1. Total leukocyte values are means ± SEM (n = 8) as analyzed by repeated measures ANOVA.
  2. *Means within a row are significantly different from unsupplemented animals (P < 0.05).