Variables | Patients received antioxidants | Patients received placebo | p value |
---|---|---|---|
 | n = 36 | n = 34 |  |
Age (y) | 62.17 ± 6.21 | 62.97 ± 5.09 | 0.559 |
Male/Female | 21/13 | 15/21 | 0.678 |
BMI | 30.10 ± 4.04 | 29.83 ± 5.06 | 0.968 |
Current smokers, n (%) | 8 (23.53%) | 10 (27.8%) | 0.684 |
Hypertension, n (%) | 25 (75.53%) | 26 (72.2%) | 0.902 |
Diabetes mellitus, n (%) | 13 (38.23%) | 9 (25%) | 0.233 |
Dyslipidemia, n (%) | 26 (76.47%) | 28 (77.8%) | 0.896 |
Obesity, n (%) | 17 (50%) | 14 (38.9%) | 0.349 |
Family history of IHD, n (%) | 26 (76.5%) | 27 (75%) | 0.886 |
Concomitant medication: | Â | Â | Â |
   Statins (%) | 25 (73.53%) | 27 (75%) | 0.888 |
   ACEIs/ARBs (%) | 19(55.88%) | 12 (33.33%) | 0.150 |
   Diuretics (%) | 6 (17.64%) | 2 (5.56%) | 0.112 |
   B-blockers (%) | 19 (55.89%) | 16 (44.4%) | 0.338 |
   CCB-blockers (%) | 10 (29.41%) | 11 (30.56%) | 0.917 |
   Aspirin (%) | 13 (38.23%) | 16 (44.45%) | 0.598 |
Baseline systolic BP (mm/Hg) | 125.2 ± 25.4 | 138.0 ± 20.8 | 0.203 |
Baseline diastolic BP (mm/Hg) | 78.4 ± 11.7 | 75.9 ± 7.8 | 0.291 |
Baseline fasting glucose (mg/dl) | 127.1 ± 52.8 | 118.9 ± 42.2 | 0.476 |
Baseline HbA1C (%) | 7.1 ± 1.7 | 6.8 ± 1.4 | 0.391 |
Baseline total cholesterol (mg/dl) | 201.5 ± 53.1 | 198.8 ± 50.8 | 0.833 |
Baseline LDL Cholesterol (mg/dl) | 117.5 ± 43.7 | 118.3 ± 47.1 | 0.945 |
Baseline HDL% | 22.1 ± 4.6 | 26.0 ± 5.4 | 0.004 |
Baseline triglycerides (mg/dl) | 189.5 ± 95.0 | 122.8 ± 56.5 | 0.001 |
Baseline hs-CRP (mg/dl) | 1.84 ± 2.9 | 1.35 ± 1.6 | 0.616 |
Baseline endothelin(fmol/ml) | 0.7 ± 2.6 | 1.4 ± 4.8 | 0.293 |
Baseline homocysteine (μmol/l) | 9.2 ± 2.8 | 8.8 ± 3.1 | 0.486 |
Baseline renin (ng/ml/hr) | 1.8 ± 3.4 | 1.5 ± 1.8 | 0.695 |
Baseline aldosteron (pg/ml) | 7.4 ± 5.6 | 6.7 ± 4.5 | 0.590 |
Baseline urine cathacholamines (mg/24 h) | 24.74 ± 22.4 | 19.5 ± 12.1 | 0.278 |