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Table 1 Baseline demographic and clinical characteristics of study patient

From: Effect of long-term treatment with antioxidants (vitamin C, vitamin E, coenzyme Q10 and selenium) on arterial compliance, humoral factors and inflammatory markers in patients with multiple cardiovascular risk factors

Variables

Patients received antioxidants

Patients received placebo

p value

 

n = 36

n = 34

 

Age (y)

62.17 ± 6.21

62.97 ± 5.09

0.559

Male/Female

21/13

15/21

0.678

BMI

30.10 ± 4.04

29.83 ± 5.06

0.968

Current smokers, n (%)

8 (23.53%)

10 (27.8%)

0.684

Hypertension, n (%)

25 (75.53%)

26 (72.2%)

0.902

Diabetes mellitus, n (%)

13 (38.23%)

9 (25%)

0.233

Dyslipidemia, n (%)

26 (76.47%)

28 (77.8%)

0.896

Obesity, n (%)

17 (50%)

14 (38.9%)

0.349

Family history of IHD, n (%)

26 (76.5%)

27 (75%)

0.886

Concomitant medication:

   

   Statins (%)

25 (73.53%)

27 (75%)

0.888

   ACEIs/ARBs (%)

19(55.88%)

12 (33.33%)

0.150

   Diuretics (%)

6 (17.64%)

2 (5.56%)

0.112

   B-blockers (%)

19 (55.89%)

16 (44.4%)

0.338

   CCB-blockers (%)

10 (29.41%)

11 (30.56%)

0.917

   Aspirin (%)

13 (38.23%)

16 (44.45%)

0.598

Baseline systolic BP (mm/Hg)

125.2 ± 25.4

138.0 ± 20.8

0.203

Baseline diastolic BP (mm/Hg)

78.4 ± 11.7

75.9 ± 7.8

0.291

Baseline fasting glucose (mg/dl)

127.1 ± 52.8

118.9 ± 42.2

0.476

Baseline HbA1C (%)

7.1 ± 1.7

6.8 ± 1.4

0.391

Baseline total cholesterol (mg/dl)

201.5 ± 53.1

198.8 ± 50.8

0.833

Baseline LDL Cholesterol (mg/dl)

117.5 ± 43.7

118.3 ± 47.1

0.945

Baseline HDL%

22.1 ± 4.6

26.0 ± 5.4

0.004

Baseline triglycerides (mg/dl)

189.5 ± 95.0

122.8 ± 56.5

0.001

Baseline hs-CRP (mg/dl)

1.84 ± 2.9

1.35 ± 1.6

0.616

Baseline endothelin(fmol/ml)

0.7 ± 2.6

1.4 ± 4.8

0.293

Baseline homocysteine (μmol/l)

9.2 ± 2.8

8.8 ± 3.1

0.486

Baseline renin (ng/ml/hr)

1.8 ± 3.4

1.5 ± 1.8

0.695

Baseline aldosteron (pg/ml)

7.4 ± 5.6

6.7 ± 4.5

0.590

Baseline urine cathacholamines (mg/24 h)

24.74 ± 22.4

19.5 ± 12.1

0.278