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Table 2 Change from baseline in homodynamic, arterial stiffness and metabolic variables in each group

From: Effect of long-term treatment with antioxidants (vitamin C, vitamin E, coenzyme Q10 and selenium) on arterial compliance, humoral factors and inflammatory markers in patients with multiple cardiovascular risk factors

Variables

Patients received antioxidants

Patients received placebo

 

baseline

6 month

p-value

baseline

6 month

p-value

Systolic BP (mm/Hg)

145.2 ± 25.4

136.1 ± 22.3

0.001

138.0 ± 20.8

135.0 ± 21.6

0.257

Diastolic BP (mm/Hg)

78.4 ± 11.7

75.0 ± 12.3

0.034

75.9 ± 7.8

75.0 ± 10.3

0.493

LAEI(ml/mm Hg × 10)

11.0 ± 4.4

12.7 ± 4.7

0.006

12.9 ± 6.2

11.3 ± 4.3

0.151

SAEI(ml/mm Hg × 100)

3.3 ± 1.9

4.7 ± 2.7

0.0001

3.6 ± 1.6

3.7 ± 1.9

0.732

SVR(dynes•sec/cm5)

1817.0 ± 751.5

1617.3 ± 305.2

0.102

1594.9 ± 351.3

1638.7 ± 311.3

0.533

Glucose(mg/dl)

127.0 ± 52

129 ± 62

0.535

118.9 ± 42

123.2 ± 55

0.496

HbA1C(%)

7.08 ± 1.69

6.33 ± 2.3

0.022

6.82 ± 1.44

6.86 ± 1.66

0.767

Total Cholesterol(mg/dl)

201.5 ± 53.1

180.7 ± 58.3

0.074

197.12 ± 50

186.80 ± 37.78

0.125

Triglycerides(mg/dl)

189 ± 94

170.4 ± 72

0.058

124.5 ± 56.5

127.83 ± 46.7

0.645

HDL%

22.1 ± 4

26.2 ± 10

0.022

26 ± 5.4

27.11 ± 5.5

0.212

LDL Cholesterol(mg/dl)

116.8 ± 44.4

103.4 ± 47

0.13

117.91 ± 47.9

109.0 ± 33.1

0.135

hs-CRP(mg/dl)

1.94 ± 3

0.62 ± 0.77

0.222

1.44 ± 1.59

0.95 ± 0.90

0.271

Renin (ng/ml/hr)

1.79 ± 3.4

2.27 ± 2.6

0.494

1.36 ± 1.55

1.91 ± 1.87

0.149

Aldosterone(pg/ml)

7.38 ± 5.6

8.2 ± 5.06

0.354

6.70 ± 4.5

7.00 ± 3.84

0.638

Homocysteine(μmol/l)

9.24 ± 2.82

9.19 ± 2.83

0.911

8.75 ± 3.04

9.11 ± 3.3

0.139

Ur cathacholamines(mg/24 h)

24.74 ± 21

28.5 ± 19

0.118

19.54 ± 12

22 ± 20

0.283