Identification of the Eph receptor pathway as a novel target for eicosapentaenoic acid (EPA) modification of gene expression in human colon adenocarcinoma cells (HT-29)

Table 4 Fold changes of key genes altered after EPA treatment in the Ephrin receptor network.

Gene of interest	Length of treatment (hr)	fold expression	Adjusted P value
EphB4	8	2.2	0.02
	24	1.8	0.02
EphA1	8	2.0	0.02
	24	1.6	0.03
Vav2	8	1.1	0.82
	24	2.2	0.01

Fold changes of key genes identified as significantly altered after EPA treatment of HT29 cells in the Ephrin receptor network. Analysis of microarray data was performed in R as detailed in the materials and methods and includes a Benjamini Hochberg false discovery rate of less than 5%. All data are expressed relative to an untreated control.

ISSN: 1743-7075