Figure 3
Leucine supplementation improves glycemic control independent of energy balance in yellow agouti ( Ay) mice. A-B: Body weight (A) and HbA1c levels (B) of the young Aymice before and after 2 and 4 months of leucine treatment. Leucine supplementation and breeder chow diet were started at 2 months of age (n = 8). C-D: Body weight (C) and HbA1c levels (D) of the old Aymice before and after 10 weeks of leucine treatment. Leucine supplementation and breeder chow diet were started at 5 months of age (n = 6). * indicates p < 0.05, control vs. leucine-treated at the end of the study.