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Figure 4 | Nutrition & Metabolism

Figure 4

From: Chronic leucine supplementation improves glycemic control in etiologically distinct mouse models of obesity and diabetes mellitus

Figure 4

Leucine supplementation improves glucose and insulin homeostasis in Aymice. A: Plasma glucose levels in the fed, basal and fast states after 4 months of leucine treatment. B: Positive correlation between HbA1c levels and plasma glucose levels in the fed state, which fits the following equation (fed glu = -392 + 116 × HbA1c, F = 18.1, Standard error of estimation 93.184, F = 18.1, p < 0.001). C-E: Plasma insulin levels in the fed, basal and fast states after 4 months of leucine treatment. * and ** indicate p < 0.05 and 0.01, control vs. leucine-treated, respectively, n = 8.

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