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Table 4 Fasting plasma lipid concentrations, glucose and insulin AUC after MTT and hepatic TG

From: Increased hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid in combination with trans-11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA-cp rat

 

Dietary groups

 

Lean control

Obese control

Obese CLA

Obese VA+CLA

TG (mmol/L)

0.47 ± 0.0c

3.28 ± 0.4a

2.05 ± 0.3*b

1.4 ± 0.1***bc

NEFA (mmol/L)

0.20 ± 0.02c

0.48 ± 0.02ab

0.57 ± 0.03a

0.42 ± 0.05b

TC (mmol/L)

2.26 ± 0.0c

6.18 ± 0.4a

4.22 ± 0.2***b

4.92 ± 0.2**b

LDL-C (mmol/L)

0.97 ± 0.1c

2.28 ± 0.2a

1.56 ± 0.1**b

1.2 ± 0.1***bc

Fasting glucose (mmol/L)

5.94 ± 0.08

6.81 ± 0.4

5.94 ± 0.36

6.75 ± 0.72

Glucose iAUC (mmol/L.h)

45.19 ± 4.5

52.22 ± 7.8

70.25 ± 14.7

42.7 ± 33.05

Fasting insulin (μIU/L)

73.41 ± 27.4b

629.2 ± 165.3a

216 ± 13.6*b

372.8 ± 98.24ab

Insulin AUC (μIU/L.h)

8739 ± 1566 c

40437 ± 4384 a

24548 ± 3465*b

23001 ± 2744*b

Insulin iAUC (μIU/L.h)

4452 ± 1464

11805 ± 7603

11585 ± 3885

4451 ± 3015

Liver TG (mmol/g protein)

2.2 ± 0.3d

21.2 ± 1.0a

16.6 ± 1.1*b

12.1 ± 1.3***c

  1. Plasma lipid and liver TG values are mean ± SEM, n = 8. Insulin AUC is mean ± SEM, n = 4. Means in the same raw with different symbol are significantly different as compared to obese control; *P < 0.05, **P < 0.01, ***P < 0.001. Means in the same raw with different letter are significantly different among control (lean and obese) and obese treated groups (CLA and VA+CLA).
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Nutrition & Metabolism

ISSN: 1743-7075

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