Rx treatment increased the adipocyte size of db/db diabetic mice. Panels show the representative images of hemotoxylin and eosin-staining of epididymal adipose tissue of (a) db/db mice treated with vehicle and (b) db/db mice treated with Rx (2 g/kg/day). (c) Quantification of the adipocyte size. Data were statistically analyzed using one-way ANOVA with Dunnette's post hoc test. Data are presented as mean ± S.E.M. (n = 5-6). * P < 0.05.