Figure 1From: Sexual dimorphism in the lasting effects of moderate caloric restriction during gestation on energy homeostasis in rats is related with fetal programming of insulin and leptin resistanceBody weight over time until the age of 5 months (A) and body fat content at the ages of 2 and 5 months (B) of male and female offspring of controls and caloric restricted dams during gestation (CR). Animals were fed with standard normal fat (NF) diet until the age of 4 months and then exposed to a high fat (HF) diet (the dotted line indicates the time point of change from NF to HF diet). Data are expressed as the mean ± SEM of 12 animals per group. Statistics: A, effect of age; RxA, interaction between caloric restriction during lactation and age (ANOVA repeated measures). #, different from their respective control group (Student's t test). The arrow indicates the starting point of significant effects on body weight in male animals.Back to article page