Glucose (mg/dl) | Insulin (μg/l) | Leptin (μg/l) | Triglycerides (mg/ml) | NEFA (μg/l) | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Control | CR | Control | CR | Control | CR | Control | CR | Control | CR | ||
MALES | |||||||||||
Ad libitum | 98 ± 4 | 95 ± 4 | 0.774 ± 0.166 | 1.44 ± 0.27# | 3.52 ± 0.43 | 3.38 ± 0.44 | 0.669 ± 0.193 | 1.48 ± 0.20# | 0.447 ± 0.054 | 0.895 ± 0.054# | |
2 month-old | 14-h fasting | 65 ± 2+ | 66 ± 3+ | 0.115 ± 0.029+ | 0.103 ± 0.026+ | 0.832 ± 0.053+ | 0.471 ± 0.086+ | 0.447 ± 0.065 | 1.30 ± 0.24# | 0.622 ± 0.077 | 1.21 ± 0.03+ # |
ANOVA | F | RxF | F | R | R,F | ||||||
Ad libitum | 73 ± 2 | 77 ± 2 | 1.44 ± 0.24 | 2.29 ± 0.60 | 7.34 ± 0.74 | 9.48 ± 0.71 | 1.25 ± 0.25 | 1.57 ± 0.13 | 0.765 ± 0.079 | 1.12 ± 0.16 | |
4 month-old | 14-h fasting | 64 ± 3+ | 72 ± 3 | 0.468 ± 0.094+ | 1.15 ± 0.29+ # | 4.23 ± 0.31+ | 4.82 ± 0.33+ | 0.636 ± 0.153+ | 1.12 ± 0.10+ # | 0.842 ± 0.144 | 1.35 ± 0.11# |
ANOVA | F | F | F | R,F | R | ||||||
Ad libitum | 77 ± 5 | 80 ± 2 | 1.47 ± 0.41 | 2.69 ± 0.68# | 8.17 ± 1.25 | 15.3 ± 1.6# | 1.06 ± 0.16 | 1.94 ± 0.23# | 1.27 ± 0.07 | 1.17 ± 0.14 | |
5 month-old | 14-h fasting | 63 ± 3+ | 65 ± 3+ | 0.583 ± 0.147+ | 1.43 ± 0.35+ # | 4.44 ± 0.78+ | 6.17 ± 0.84+ | 1.02 ± 0.21 | 1.31 ± 0.21+ | 1.20 ± 0.10 | 1.26 ± 0.07 |
ANOVA | F | R,F | RxF | R | |||||||
FEMALES | |||||||||||
Ad libitum | 92 ± 3 | 100 ± 5 | 0.657 ± 0.115 | 1.55 ±0.35# | 3.38 ± 0.44 | 2.87 ± 0.32 | 0.373 ± 0.063 | 0.946 ± 0.142# | 0.529 ± 0.057 | 0.921 ± 0.047# | |
2 month-old | 14-h fasting | 71 ± 2+ | 71 ± 3+ | 0.134 ± 0.019+ | 0.134 ±0.014+ | 0.448 ± 0.055+ | 0.511 ± 0.129+ | 0.516 ± 0.148 | 0.633 ± 0.217 | 0.657 ± 0.085 | 1.28 ± 0.11+ # |
ANOVA | F | RxF | F | R | R,F | ||||||
Ad libitum | 84 ± 6 | 82 ± 2 | 1.27 ± 0.16 | 1.86 ±0.35 | 5.59 ± 0.26 | 6.31 ± 0.37 | 0.747 ± 0.176 | 1.66 ± 0.38# | 0.715 ± 0.090 | 1.35 ± 0.15# | |
4 month-old | 14-h fasting | 67 ± 3+ | 67 ± 1+ | 0.246 ± 0.045+ | 0.465 ±0.120+ | 2.03 ± 0.17+ | 2.09 ± 0.10+ | 0.496 ± 0.119+ | 0.693 ± 0.102+ | 0.826 ± 0.105 | 1.26 ± 0.08# |
ANOVA | F | F | F | R,F | R | ||||||
Ad libitum | 80 ± 1 | 81 ± 3 | 1.47 ± 0.19 | 2.34 ± 0.33# | 7.21 ± 0.67 | 6.21 ± 0.449 | 0.909 ± 0.290 | 1.44 ± 0.30 | 0.957 ± 0.068 | 1.10 ± 0.09 | |
5 month-old | 14-h fasting | 69 ± 2+ | 60 ± 3+ # | 0.251 ± 0.033+ | 0.476 ± 0.103+ | 2.98 ± 0.20+ | 3.25 ± 0.162+ | 1.14 ± 0.32 | 1.19 ± 0.29 | 1.17 ± 0.09 | 1.30 ± 0.12 |
ANOVA | F | R, F | F |