Effects of olive oil and its fractions on oxidative stress and the liver's fatty acid composition in 2,4-Dichlorophenoxyacetic acid-treated rats

Table 3 Effects of extra virgin olive oil (EVOO) and its fractions (OOHF and OOLF) on biochemical indicators of liver function (AST, ALT, ALP, γ-GT and total bilirubin) in serum of rat treated or not with 2,4-D.

Groups	AST (U/L)	ALT (U/L)	ALP (U/L)	γ-GT (U/L)	T-Bilirubin (U/I)
C	96.40 ± 17.07	33.75 ± 3.24	109.80 ± 13.62	20.20 ± 3.76	5.66 ± 1.18
D	138.16 ± 12.44^§§	57.50 ± 10.60^§§	157.57 ± 27.09^§§	32.00 ± 2.94^§§	12.05 ± 0.81^§§
D/EVOO	97.71 ± 13.57‍ **	38.00 ± 3.16**	123.33 ± 20.81	34.14 ± 5.81^§§	7.00 ± 0.91**
D/OOHF	94.16 ± 10.72**	35.40 ± 3.20**	127 ± 23.64	30.14 ± 12.40	7.56 ± 1.70**^§
D/OOLF	103.50 ± 12.55**	31.28 ± 4.46**	194.25 ± 12.81**^§§	34.60 ± 12.09^§	7.42 ± 0.61**^§
EVOO	94.60 ± 6.69	34.83 ± 4.35	107.00 ± 24.73	25.00 ± 8.64	6.14 ± 1.09
OOHF	95.83 ± 10.79	29.44 ± 3.43	123.60 ± 28.83	22.57 ± 7.36	6.86 ± 1.33
OOLF	96.37 ± 9.85	32.66 ± 3.44	119.00 ± 10.98	30.60 ± 7.16^§	5.58 ± 1.68

Student t test (C: controls group, D: 2,4-D treated group, D/EVOO: 2,4-D plus extra virgin olive oil, D/OOHF: 2,4-D plus hydrophilic fraction, D/OOLF: 2,4-D plus lipophilic fraction, EVOO: extra virgin olive oil treated group alone, OOHF: group treated with hydrophilic fraction of olive oil, OOLF: group treated with lipophilic fraction of olive oil.
** p <.01; * p < .05 (compared to Group D)
^§§ p < .01; ^§ p < .05 (compared to controls C)

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