Table 1 Baseline characteristics of the patients
| Â | Non-obese | Obese | Â |
|---|---|---|---|
| Â | (n = 108) | (n = 105) | P |
Body mass index (kg/m2) | 22.7 ± 1.7 | 28.4 ± 2.9 | <0.01 |
Age (years) | 64 ± 7 | 59 ± 10 | <0.01 |
Men (%) | 49 | 52 | 0.63 |
Duration of diabetes mellitus (years) | 12 ± 9 | 8 ± 7 | <0.01 |
Current plus past smoking (%) | 62 | 67 | 0.59 |
Current drinkers (%) | 58 | 60 | 0.79 |
Therapeutic method for diabetes mellitus | Â | Â | Â |
   Diet only/OHAs/Insulin (%) | 16/67/18 | 31/48/21 | <0.01 |
Systolic blood pressure (mmHg) | 132 ± 16 | 137 ± 16 | 0.01 |
Diastolic blood pressure (mmHg) | 78 ± 10 | 81 ± 11 | 0.02 |
Hypertension (%) | 61 | 87 | <0.01 |
Total cholesterol (mmol/L) | 5.3 ± 1.1 | 5.3 ± 1.1 | 0.71 |
LDL cholesterol (mmol/L) | 2.9 ± 0.7 | 3.1 ± 0.8 | <0.01 |
HDL cholesterol (mmol/L) | 1.6 ± 0.5 | 1.4 ± 0.3 | 0.09 |
Hyperlipidaemia (%) | 81 | 84 | 0.52 |
Haemoglobin A1c (%) | 8.1 ± 2.0 | 8.1 ±1.7 | 0.90 |
Uric acid (μmol/L) | 282 ± 84 | 302 ± 79 | 0.10 |
Serum creatinine (μmol/L) | 67 ± 17 | 67 ± 15 | 0.71 |
Estimated GFR (mL/min/1.73 m2) | 72.6 ± 17.3 | 75.5 ± 17.7 | 0.25 |
Initial dose of metformin (mg/day) | 556 ± 110 | 566 ± 116 | 0.49 |