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Table 2 HbA1c reduction determinants by correlation coefficient

From: Long-term effect of metformin on blood glucose control in non-obese patients with type 2 diabetes mellitus

 

1 year

2 years

3 years

 

r

P

r

P

r

P

Sex

0.06

0.42

-0.07

0.42

-0.15

0.14

Age

0.11

0.60

-0.02

0.79

0.14

0.16

Duration of diabetes

0.24

<0.01

0.16

0.10

0.15

0.21

Body mass index

-0.04

0.54

-0.04

0.61

-0.10

0.34

HbA1c at baseline

-0.81

<0.01

-0.73

<0.01

-0.82

<0.01

Hypertension

-0.09

0.19

-0.01

0.93

-0.01

0.91

Hyperlipidaemia

-0.02

0.75

-0.04

0.65

0.23

0.47

Estimated GFR

0.03

0.69

0.04

0.63

0.04

0.67

Therapeutic method

0.13

0.07

0.17

0.10

0.11

0.27

Initial dose of metformin

-0.11

0.11

0.01

0.94

-0.03

0.75

Metformin dose at 1 year

-0.07

0.32

0.08

0.36

-0.01

0.86

  1. GFR: glomerular filtration rate.
  2. Sex (man = 1, woman = 2), therapeutic method (diet = 1, oral hypoglycemic agents = 2, insulin = 3), hypertension (absent = 0, present = 1) and hyperlipidaemia (absent = 0, present = 1) were replaced with a number.