Table 1 Preventive effects of hepatocarcinogenesis of red raspberry extract in a Wistar rat model a
From: Fresh raspberry phytochemical extract inhibits hepatic lesion in a Wistar rat model
Group | no. | DEN | dose (g/kg of b.w.) | no. of rats with nodules/total no. of rats | nodule incidence (%) | liver index (g/100 g b.w.) (mean ± S.D.) |
|---|---|---|---|---|---|---|
High | 20 | + | 3.0 | 1/20 | 5.0** | 2.61 ± 0.49 |
Middle | 20 | + | 1.5 | 5/20 | 25.0* | 2.66 ± 0.18 |
Low | 20 | + | 0.75 | 8/20 | 40.0 | 2.78 ± 0.50 |
Control - | 20 | - | - | 0/20 | 0.0 | 2.90 ± 0.78* |
Control + | 20 | + | - | 9/20 | 45.0 | 2.54 ± 0.23 |