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Table 2 Direct relationships (1 jump) between seed proteins of ketogenic-diet map and type 2 diabetes effector proteins.

From: Revealing the molecular relationship between type 2 diabetes and the metabolic changes induced by a very-low-carbohydrate low-fat ketogenic diet

Physiologic Pathway Type 2 Diabetes Effector Protein (Protein Name) Gene Name (synonyms)
Insufficient insulin production Somatotropin GH1
  Solute carrier family 2, facilitated glucose transporter member 4 (GLUT4) SLC2A4 (GLUT4)
  E3 ubiquitin-protein ligase CBL (CBL) CBL (CBL2, RNF55)
  Protein kinase C alpha type (PRKCA) PRKCA (PKCA, PRKACA)
Insulin resistance Nuclear factor NF-kappa-B p105 subunit (NFKβ) NFKB1
  Insulin receptor substrate 1 (IRS-1) IRS1
  Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1-α) PPARGC1A (LEM6, PGC1, PGC1A, PPARGC)
  Protein kinase Akt-3 (PKBγ) AKT3 (PKBG)