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Table 1 Golden-Syrian hamsters fed cholesterol and SFA-supplemented non-purified diets compared to chow.

From: Use of hamster as a model to study diet-induced atherosclerosis

         Chow mg/dL    SFA mg/dL   
Ref Strain Age (weeks) Study Length (weeks) % Fat (w/w) % CH (w/w) HDL-C nHDL-C nHDL-C:HDL-C TG HDL-C nHDL-C nHDL-C:HDL-C TG Lesion Lesion Measure
[38] F1B 8 5 101 0.05     150     650 Aorta stained (μ2)
[31] F1B 8 8 102 0.05 58 58 1.0 87 88 234 2.7 216 Foam cells/mm2 aorta
[55] F1B 8 12 103 0.1 48 35 0.7 110 67 444 6.6 545 CE (ug)/aorta (mg wet weight)
[55] CR 8 12 103 0.1 68 67 1.0 129 86 210 2.4 195 CE (ug)/aorta (mg wet weight)
[49] CR 10 24 53 2 50 47 0.9 186 247 581 2.4 1912 Fatty streak area (%)
[47] CR 8 6 102 0.1 71 25 0.4 219 108 112 1.0 341 Aorta with lesion (% )
[47] CR 8 6 103 0.1 71 25 0.4 219 108 174 1.6 301 Aorta with lesion (% )
[58] UNK 3-4 28 53 1     120     169 EC (ug)/aorta (10mg dry weight)
[50] UNK 5 40 102 0.3 87 64 0.7 102 153 224 1.5 295 Fatty streak area (%)
  1. SFA: saturated fatty acid; CH: cholesterol; HDL-C: high-density lipoprotein cholesterol; nHDL-C: non-HDL-C; TG: triglycerides; CR: Charles River; UNK: unknown hamster strain; EC: esterified cholesterol. SFA source: 1Hydrogenated coconut oil, 2Coconut oil and 3Butter