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Table 5 Phospholipid and ceramide levels in the feces of mice fed the high-fat diet alone (HF) or the high-fat diet supplemented with milk phospholipids (HFPL) in the form of phospholipid-rich dairy milk extract (PLRDME)

From: Hepatic accumulation of intestinal cholesterol is decreased and fecal cholesterol excretion is increased in mice fed a high-fat diet supplemented with milk phospholipids

 

HF

HFPL

difference

nmol/mouse/day

   

Phosphatidylcholine

71 ± 7

272 ± 22 ***

+281%

Lysophosphatidylcholine

60 ± 7

92 ± 8 **

+52%

Phosphatidylethanolamine

7 ± 1

13 ± 1 **

+79%

Phosphatidylinositol

3.1 ± 0.4

22.5 ± 2.6 ***

+617%

Phosphatidylserine

3.3 ± 0.3

4.8 ± 0.4 *

+43%

Sphingomyelin

55 ± 5

362 ± 34 ***

+560%

Ceramide

29 ± 2

150 ± 13 ***

+424%

Monohexosylceramide

10 ± 1

100 ± 8 ***

+934%

Dihexosylceramide

23 ± 1

258 ± 15 ***

+1017%

Trihexosylceramide

0.8 ± 0.1

2.5 ± 0.2 ***

+212%

  1. Results represent means ± SEM for 11 fecal samples in each group. Percentage difference between groups is given in italics. Significant difference between HF and HFPL by Student's t-test: * P < 0.05, ** P < 0.01, *** P < 0.001.