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Table 1 Area under the curve during an oral glucose tolerance test (mean ± SE) following ingestion of chlorogenic acid, decaffeinated coffee, trigonelline and placebo in 15 healthy overweight men.

From: Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones

  TOTAL GLP-1 INTACT GLP-1* GIP
   (pmol/L × 120 min)  
Placebo 1720 ± 180 83 ± 33 6984 ± 566**
Chlorogenic acid 1549 ± 178 140 ± 47 6656 ± 620
Decaffeinated coffee 1809 ± 152 66 ± 21 6725 ± 516
Trigonelline 1730 ± 160 94 ± 39 7512 ± 619
  1. *Intact GLP-1 concentrations were very low and a substantial number was at the limit of detection and were reported as zero.
  2. **n = 14 (1 missing value at time point 15 min.)