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Table 1 Area under the curve during an oral glucose tolerance test (mean ± SE) following ingestion of chlorogenic acid, decaffeinated coffee, trigonelline and placebo in 15 healthy overweight men.

From: Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones

 

TOTAL GLP-1

INTACT GLP-1*

GIP

  

(pmol/L × 120 min)

 

Placebo

1720 ± 180

83 ± 33

6984 ± 566**

Chlorogenic acid

1549 ± 178

140 ± 47

6656 ± 620

Decaffeinated coffee

1809 ± 152

66 ± 21

6725 ± 516

Trigonelline

1730 ± 160

94 ± 39

7512 ± 619

  1. *Intact GLP-1 concentrations were very low and a substantial number was at the limit of detection and were reported as zero.
  2. **n = 14 (1 missing value at time point 15 min.)