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Figure 4 | Nutrition & Metabolism

Figure 4

From: Glycated albumin suppresses glucose-induced insulin secretion by impairing glucose metabolism in rat pancreatic β-cells

Figure 4

Effects of glyceraldehyde, DHA, α-KIC, and methylpyruvate on insulin secretion. (A) Rat islets were incubated for 24 h at 37°C with 0.1 mg/mL HA (white bar) or GA (black bar), in the presence of 10 mM glyceraldehyde or 10 mM DHA, under the G3 condition. Each bar represents the mean plus SEM of 3 separate experiments, each with n = 5. (B) Rat islets were incubated for 24 h at 37°C with 0.1 mg/mL HA (white bar) or GA (black bar), in the presence of 10 mM α-KIC or 10 mM methylpyruvate, under the G3 or G15 condition. Each bar represents the mean plus SEM of 3 separate experiments, each with n = 5. ss; statistically significant.

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