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Table 3 Effects of compounds on gene expression of adipocyte differentiation markers and enzymes involved in fat and glucose metabolism (n = 6 - 15)

From: Dietary constituents reduce lipid accumulation in murine C3H10 T1/2 adipocytes: A novel fluorescent method to quantify fat droplets

  

PUFAs

CAROTENOIDS

PHENOLS

  

DHA

25 μM

EPA

25 μM

lycopene

2 μM

β-carotene

2 μM

EGCG

25 μM

HT

25 μM

Resv

25 μM

PPARγ2

fold

0.48

0.61

0.93

0.48

0.97

0.53

1.07

 

error +/-

0.11/0.09

0.09/0.08

0.33/0.25

0.17/0.13

0.20/0.17

0.15/0.12

0.12/0.11

 

p-value

< 0.001

0.002

0.75

0.04

0.64

< 0.001

0.53

PPARα

fold

0.15

0.25

1.01

0.80

0.81

0.47

0.92

 

error +/-

0.10/0.06

0.10/0.07

0.57/0.36

0.37/0.25

0.11/0.09

0.15/0.12

0.07/0.07

 

p-value

< 0.001

< 0.001

0.94

0.69

0.33

< 0.001

0.99

C/EBPα

fold

0.60

0.82

0.86

0.42

1.02

0.46

1.12

 

error +/-

0.09/0.08

0.08/0.07

0.34/0.24

0.29/0.17

0.13/0.12

0.15/0.11

0.07/0.07

 

p-value

< 0.001

0.038

0.12

0.02

0.94

< 0.001

0.44

aP2

fold

0.52

0.72

1.09

0.31

0.82

0.47

1.06

 

error +/-

0.13/0.11

0.05/0.05

0.13/0.12

0.25/0.14

0.07/0.07

0.15/0.11

0.07/0.06

 

p-value

< 0.001

0.005

0.26

0.007

0.04

< 0.001

0.45

Acrp30

fold

0.41

0.61

0.85

0.39

0.84

0.69

1.11

 

error +/-

0.13/0.10

0.12/0.10

0.11/0.10

0.39/0.19

0.09/0.08

0.08/0.07

0.14/0.13

 

p-value

< 0.001

0.002

0.06

0.02

0.79

< 0.001

0.11

Glut4

fold

0.25

0.39

1.33

0.37

0.86

0.42

1.04

 

error +/-

0.10/0.07

0.09/0.08

0.21/0.18

0.42/0.20

0.17/0.15

0.07/0.06

0.20/0.17

 

p-value

< 0.001

< 0.001

0.04

0.06

0.33

< 0.001

0.47

LPL

fold

0.39

0.62

0.41

0.10

0.63

0.77

0.73

 

error +/-

0.17/0.12

0.13/0.10

0.35/0.19

0.40/0.08

0.28/0.19

0.12/0.11

0.59/0.33

 

p-value

< 0.001

0.013

0.09

0.005

0.01

0.13

0.18

FAS

fold

0.63

0.65

0.79

0.68

1.13

0.83

1.05

 

error +/-

0.05/0.05

0.05/0.05

0.19/0.15

0.06/0.06

0.19/0.17

0.07/0.07

0.07/0.07

 

p-value

< 0.001

0.02

0.14

0.04

0.37

0.08

0.37

HSL

fold

0.58

0.75

0.91

0.49

1.04

0.69

1.05

 

error +/-

0.11/0.09

0.11/0.10

0.06/0.06

0.28/0.18

0.10/0.09

0.09/0.08

0.07/0.07

 

p-value

< 0.001

0.016

0.58

0.04

0.69

< 0.001

0.30

CPT-1β

fold

0.21

0.34

1.11

0.59

0.81

0.44

0.84

 

error +/-

0.09/0.06

0.11/0.08

0.28/0.22

0.27/0.18

0.10/0.09

0.06/0.05

0.09/0.08

 

p-value

< 0.001

< 0.001

0.23

0.35

0.08

< 0.001

0.47

ACC1

fold

0.57

0.64

0.90

0.88

1.46

0.68

1.17

 

error +/-

0.14/0.11

0.14/0.11

0.30/0.23

0.01/0.01

0.34/0.27

0.15/0.13

0.19/0.17

 

p-value

0.004

0.02

0.58

0.72

0.09

0.02

0.45

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Nutrition & Metabolism

ISSN: 1743-7075

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