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Figure 1 | Nutrition & Metabolism

Figure 1

From: The Regulation of Leptin, Leptin Receptor and Pro-opiomelanocortin Expression by N-3 PUFAs in Diet-Induced Obese Mice Is Not Related to the Methylation of Their Promoters

Figure 1

Regions of the mouse leptin, leptin-R and POMC promoters. The CG dinucleotides are underlined and letters (a to r) were assigned to each of the analyzed CGs. (A) The leptin promoter sequence with CpG islands spanning nucleotides -324 to -29. (B) The leptin-R promoter sequence with CpG islands spanning nucleotides -633 to -345. (C) The POMC promoter sequence with CpG islands spanning nucleotides -451 to -167.

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