Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity

Table 9 ATP, NADH, NADPH, and CoQ10 The average levels measured in the Autism and Neurotypical groups are reported below, along with their standard deviations

	Units	Autism Group	Neuro-typical Group	% Difference	p-value	Neurotypical Reference Range (10^th and 90^th percentiles)	Autism Group % below RR	Autism Group % above RR
ATP (plasma)	nmol/l	14.5 +/- 4.2	18.5 +/- 4.8	-22%	< 0.0001 *	13.21	36%	4%
NADH (RBC)	nmol/ml	15.3 +/- 4.1	20.7 +/- 4.3	-26%	< 0.0001 *	16-25	51%	2%
NADPH (RBC)	nmol/ml	22.6 +/- 6.1	30.9 +/- 8.5	-27%	< 0.0001 *	20-40	37%	2%
CoQ10 (plasma)	μg/ml	0.55 +/- 0.15	0.60 +/- 0.16		n.s.	0.4-0.8	9%	2%

The p-value for a t-test comparison of the two groups is also reported. If the p-value is below 0.05, then the % difference between the groups is reported, and the result is highlighted.
The table also lists the reference range of the neurotypical group (10^th and 90^th percentiles), and the % of the Autism group who are above or below the reference ranges. Note that if the groups were identical, 10% would be above and 10% would be below. Percentages above 25% are highlighted.
* Statistically significant difference between the two groups with 95% confidence per Bonferroni analysis.

ISSN: 1743-7075