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Figure 6 | Nutrition & Metabolism

Figure 6

From: Dietary cholesterol, female gender and n-3 fatty acid deficiency are more important factors in the development of non-alcoholic fatty liver disease than the saturation index of the fat

Figure 6

Expression of inflammatory genes in livers of mice fed the respective high-fat diets. Cd68 mRNA expression is depicted in panel A, Tnf-α mRNA expression in panel B, and Ccl2 mRNA expression in panel C. Levels are normalized with 18S rRNA concentration and expressed as means ± SEM. Different letters indicate a significant difference (P < 0.05) within each group. GT: genotype; n.s.: non significant. In panel D the expression of Tnf-α is correlated with Cd68 expression; in panels E and F, the expressions of Cd68 and Tnf-α are correlated with plasma cholesterol (grey: male, black; female), respectively. Note that the positive correlations in panels E and F are only seen in female mice.

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Nutrition & Metabolism

ISSN: 1743-7075

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