Hepatic mRNA pattern. (A) PGC1α: peroxisome proliferator-activated receptor gamma coactivator α, (B) CPT1: carnitine palmitoyl transferase 1, (C) PPARα: peroxisome proliferator-activated receptor α, (D) FAS: fatty acid synthase. Results are expressed as relative expression. Data are the mean ± SEM. *: mean values significantly different (P < 0.05, Student's t-test). -3/+: mice fed with a control diet (n = 9), n-3/+ FOS: mice fed a control diet and supplemented with a prebiotic for 24 days (n = 10), n-3/-: mice fed an n-3 PUFA-depleted diet (n = 12), n-3/- FOS: mice fed an n-3 PUFA-depleted diet and supplemented with a prebiotic for 24 days (n = 12). The results have been partly reported in reference 20.