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Table 3 Liver weight, triglycerides and cholesterol content and plasma triglycerides and cholesterol concentration

From: Involvement of gut microbial fermentation in the metabolic alterations occurring in n-3 polyunsaturated fatty acids-depleted mice

  n-3/+ n-3/+ FOS n-3/- n-3/- FOS
Liver weight (g/100 g body weight) 4.50 ± 0.15 3.80 ± 0.11* 3.97 ± 0.08* 3.89 ± 0.05
Hepatic triglycerides content (nmol/mg proteins) 97.6 ± 10.0 115.3 ± 11.9 159.3 ± 15.4* 176.6 ± 14.5
Hepatic cholesterol content (nmol/mg proteins) 37.1 ± 2.6 43.3 ± 1.9 42.6 ± 1.8 40.8 ± 2.2
Plasma triglycerides concentration (mM) 0.41 ± 0.4 0.34 ± 0.03 0.35 ± 0.04 0.35 ± 0.03
Plasma cholesterol concentration (mM) 1.04 ± 0.05 1.00 ± 0.02 1.49 ± 0.04* 1.37 ± 0.08
  1. Data are the mean ± SEM.
  2. *: mean values significantly different from n-3/+ mice (P < 0.05, Student's t-test).
  3. #: mean values significantly different from n-3/- mice (P < 0.05, Student's t-test).
  4. -3/+: mice fed with a control diet (n = 9), n-3/+ FOS: mice fed a control diet and supplemented with a prebiotic for 24 days (n = 10), n-3/-: mice fed an n-3 PUFA-depleted diet (n = 12), n-3/- FOS: mice fed an n-3 PUFA-depleted diet and supplemented with a prebiotic for 24 days (n = 12).
  5. The results have been partly reported in reference 20.